Chloroacetyl chloride → 6,8-Dichloro-7-ethyl-4H-benzo[1,4]oxazin-3-one
反応式
[NH2:1][C:2]1[C:7]([OH:8])=[C:6]([Cl:9])[C:5]([CH2:10][CH3:11])=[C:4]([Cl:12])[CH:3]=1.Cl[CH2:14][C:15](Cl)=[O:16].C([O-])([O-])=O.[K+].[K+]>>[Cl:12][C:4]1[C:5]([CH2:10][CH3:11])=[C:6]([Cl:9])[C:7]2[O:8][CH2:14][C:15](=[O:16])[NH:1][C:2]=2[CH:3]=1参加物
4
実験手順
6-Amino-2,4-dichloro-3-ethylphenol (95MF2226) (0.293 g, 1.5 mmol), 2-chloroacetyl chloride (0.19 g, 1.7 mmol) and K2CO3 (0.44 g, 3.2 mmol) were mixed according to GP1 to give the title compound as a crude (95MF46) (0.34 g).
出典と根拠
- ORDレコード
- ord-aef3c742785646b095d43abe83d69c52
- 出典データセット
- uspto-grants-2014_03
- 特許番号
- US08680115B2
反応ノート
読み込み中…