Ethylenediamine → 4-(5-(4-(3-(4,5-Dihydro-1H-imidazol-2-yl)propyl)phenyl)-8-oxo-6-thioxo-5,7-diaza-spiro[3.4]octan-7-yl)-2-(trifluoromethyl)benzonitrile

反応式

[O:1]=[C:2]1[C:6]2([CH2:9][CH2:8][CH2:7]2)[N:5]([C:10]2[CH:15]=[CH:14][C:13]([CH2:16][CH2:17][CH2:18][CH:19]=O)=[CH:12][CH:11]=2)[C:4](=[S:21])[N:3]1[C:22]1[CH:29]=[CH:28][C:25]([C:26]#[N:27])=[C:24]([C:30]([F:33])([F:32])[F:31])[CH:23]=1.[CH2:34]([NH2:37])[CH2:35][NH2:36].BrN1C(=O)CCC1=O>ClCCl>[NH:36]1[CH2:35][CH2:34][N:37]=[C:19]1[CH2:18][CH2:17][CH2:16][C:13]1[CH:12]=[CH:11][C:10]([N:5]2[C:4](=[S:21])[N:3]([C:22]3[CH:29]=[CH:28][C:25]([C:26]#[N:27])=[C:24]([C:30]([F:33])([F:32])[F:31])[CH:23]=3)[C:2](=[O:1])[C:6]32[CH2:7][CH2:8][CH2:9]3)=[CH:15][CH:14]=1