(L)-alpha-terpineol → p-MENTHAN-8-OL

HRID 1194903ノート

反応式

HRID 1194903 の反応式
[CH3:1][C:2]1[CH2:7][CH2:6][C@H:5]([C:8]([OH:11])([CH3:10])[CH3:9])[CH2:4][CH:3]=1>C(O)C.[Pd]>[CH3:1][CH:2]1[CH2:7][CH2:6][CH:5]([C:8]([OH:11])([CH3:10])[CH3:9])[CH2:4][CH2:3]1

参加物

4

反応物 1

HCID 443162(L)-alpha-terpineol

生成物 1

HCID 10353p-MENTHAN-8-OL収率 94.9%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

α-Terpineol (6.17 g) in ethanol (130 ml) was hydrogenated for 1 h at atmospheric pressure using 10% Pd-C catalyst (290 mg). The catalyst was then removed by filtration through Kieselguhr and the solvent was removed under reduced pressure to leave the title compound as an oil (5.93 g). Distillation gave an oil (4.56 g) b.p. (13 mm) 98°; νmax (film) 3375, 2940, 1445, 1160, 1140, and 910 cm-1 ; δH (60 MHz, CDCl3) 0.6-2.0(m).

後処理

  1. customThe catalyst was then removed by filtration through Kieselguhr
  2. customthe solvent was removed under reduced pressure

出典と根拠

ORDレコード
ord-4b9d6171069e41a4b5afc1ec3971a343
出典データセット
uspto-grants-1989_03
特許番号
US04816452

反応ノート

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