Hydrochloric Acid → HCID 178517464、化合物

反応式

C(OC([C:6]1[CH:15]=[CH:14][CH:13]=[CH:12][C:7]=1[C:8](=[N:10][OH:11])[NH2:9])=O)C.[OH-].[Na+].O.Cl.[CH2:20]([OH:22])C>>[C:7]1([C:8]2[N:9]=[C:20]([OH:22])[O:11][N:10]=2)[CH:6]=[CH:15][CH:14]=[CH:13][CH:12]=1

参加物

反応物 5

HCID 313Hydrochloric Acid

HCID 702Ethanol

HCID 962Water

HCID 14798Sodium Hydroxide

HCID 86745772o-Ethoxycarbonylbenzamidoxime

生成物 1

HCID 178517464HCID 178517464、化合物

実験手順

In accordance with the known process [Yakugaku Zasshi, 84(11), 1061 (1964)], 27 g (0.13 mol) of o-ethoxycarbonylbenzamidoxime were added to a liquid mixture consisting of 10 g (0.25 mol) of sodium hydroxide, 600 ml of water and 150 ml of ethyl alcohol, followed by stirring at room temperature for 3 hours. The reaction mixture was neutralized with dilute hydrochloric acid. Crystals thus formed were collected by filtration and then washed with water, whereby the title compound was obtained as colorless crystals.