p-Toluenesulfonic acid → HCID 19896184、化合物

HRID 1196746ノート

反応式

HRID 1196746 の反応式
O.[O:2]=[CH:3][C:4]([Cl:7])([Cl:6])[Cl:5].[CH2:8]([OH:13])[CH2:9][CH:10]([CH3:12])[CH3:11].[CH3:14][C:15]1[CH:20]=CC(S(O)(=O)=O)=[CH:17][CH:16]=1>C1C=CC=CC=1>[CH2:17]([O:2][CH:3]([O:13][CH2:8][CH2:9][CH:10]([CH3:12])[CH3:11])[C:4]([Cl:7])([Cl:6])[Cl:5])[CH2:16][CH:15]([CH3:20])[CH3:14]

参加物

5

反応物 3

HCID 6101p-Toluenesulfonic acidHCID 31260Isoamyl AlcoholHCID 205283762,2,2-Trichloroacetaldehyde hydrate

生成物 1

HCID 19896184HCID 19896184、化合物

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

実験手順

A mixture of 5 g of chloral-hydrate, 10 g of isoamyl-alcohol, 0.1 g of 4-methyl-benzene-sulphonic acid and 50 ml of benzene is kept at reflux temperature and the formed water is separated by means of a Dean-Stark apparatus. After a reaction time of 9 hours the benzene is washed with a sodium-hydrogen-carbonate solution and water, dried on magnesium sulfate, then vacuum distilled.

後処理

  1. temperatureat reflux temperature
  2. customthe formed water is separated by means of a Dean-Stark apparatus
  3. washAfter a reaction time of 9 hours the benzene is washed with a sodium-hydrogen-carbonate solution and water
  4. customdried on magnesium sulfate
  5. distillationvacuum distilled

出典と根拠

ORDレコード
ord-85812d933c214b1b86bac748c720cff6
出典データセット
uspto-grants-1992_05
特許番号
US05116402

反応ノート

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