反応式
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.[F:9][B-](F)(F)F.F[N+]1C(C(Cl)(Cl)Cl)=CC=CC=1Cl>ClC(Cl)CCl>[F:9][C:6]1[CH:7]=[C:2]([Br:1])[CH:3]=[CH:4][C:5]=1[OH:8]参加物
4
反応条件
- 温度
- 45 °C
実験手順
A mixture of 0.86 g of 4-bromophenol, 1.67 g of N-fluoro-2-chloro-6-(trichloromethyl)pyridinium fluoroborate, and 40 ml of 1,1,2-trichloroethane was placed in a 100 ml 3-necked round bottomed flask equipped with a magnetic stirring bar, a thermometer, and a reflux condenser. The mixture was heated to 45° C. and allowed to react at that temperature for 23 hours under nitrogen. The mixture was then allowed to cool. Analysis by standardized gas-liquid chromatography using a mass spectrometer detector indicated that the title product was present in 74 percent conversion. The product identity was confirmed by its known 19F and 1H NMR spectra.
後処理
- customwas placed in a 100 ml 3-necked round bottomed flask
- customequipped with a magnetic stirring bar
- customto react at that temperature for 23 hours under nitrogen
- temperatureto cool
出典と根拠
- ORDレコード
- ord-977018f7e36448daaa81fb7e1e754ecd
- 出典データセット
- uspto-grants-1992_05
- 特許番号
- US05116982
関連ノート
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