Water → N'-t-butyl-N-(thiobenzoyl)hydrazine

HRID 1197253

反応式

HRID 1197253 の反応式
[C:1]([S:9]CC(O)=O)(=S)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.[C:15]([NH:19][NH2:20])([CH3:18])([CH3:17])[CH3:16].O>N1C=CC=CC=1>[C:15]([NH:19][NH:20][C:1](=[S:9])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1)([CH3:18])([CH3:17])[CH3:16]

参加物

5

反応物 3

HCID 962WaterHCID 70336((Phenylthioxomethyl)thio)acetic acidHCID 81889tert-Butylhydrazine monohydrochloride

生成物 1

HCID 19367775N'-t-butyl-N-(thiobenzoyl)hydrazine

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

反応条件

温度
120 °C

実験手順

S-(thiobenzoyl)thioglycolic acid (3.0 g) was dissolved in 20 ml pyridine, treated with t-butyl hydrazine hydrochloride (excess, ca. 4 g) and then was heated at ca. 120° C. for 14 hours. Water (120 ml) was added and the mixture was extracted with ether. The organic extracts were dried over anhydrous magnesium sulfate, filtered and evaporated to give crude N'-t-butyl-N-(thiobenzoyl)hydrazine as a viscous yellow oil.

後処理

  1. extractionthe mixture was extracted with ether
  2. dry with materialThe organic extracts were dried over anhydrous magnesium sulfate
  3. filtrationfiltered
  4. customevaporated

出典と根拠

ORDレコード
ord-f3d5cb92b44c44d88abf27a24f4af34a
出典データセット
uspto-grants-1992_05
特許番号
US05117057

関連ノート

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