Aluminium lithium hydride → 3-PHENANTHRENOL, 1,2,3,4,4A,9,10,10A-OCTAHYDRO-4
反応式
[NH:1]1[C:8]23[CH2:17][CH:4]([CH2:5][CH2:6][CH:7]2[CH2:16][CH2:15][C:14]2[C:9]3=[CH:10][CH:11]=[CH:12][CH:13]=2)[O:3][C:2]1=O.[H-].[Al+3].[Li+].[H-].[H-].[H-]>C1COCC1>[CH3:2][NH:1][C:8]12[C:9]3[C:14](=[CH:13][CH:12]=[CH:11][CH:10]=3)[CH2:15][CH2:16][CH:7]1[CH2:6][CH2:5][CH:4]([OH:3])[CH2:17]2参加物
4
実験手順
A solution of the compound from Example 62 (1.4 g, 5.75 mmol) in 20 ml THF was added to a slurry of lithium aluminum hydride (1 g) in 30 ml THF. After stirring overnight, additional lithium aluminum hydride was added (1 g) and stirring continued 3 hours. Workup afforded the title compound as a white solid (1.1 g, 83%), mp 141°-143° C.
後処理
- stirringstirring continued 3 hours
出典と根拠
- ORDレコード
- ord-d800dc629c6842959016620750708ad8
- 出典データセット
- uspto-grants-1994_01
- 特許番号
- US05276053
反応ノート
読み込み中…