4-Chlorostyrene → 1-[Dimethyl(1-methylethoxy)silyl]-4-ethenylbenzene

HRID 1197900

反応式

[CH:1]([O:4][Si:5]([CH3:8])([CH3:7])Cl)([CH3:3])[CH3:2].[CH:9]([C:11]1[CH:16]=[CH:15][C:14]([Mg]Cl)=[CH:13][CH:12]=1)=[CH2:10].C(C1C=CC(Cl)=CC=1)=C.[Mg]>C1COCC1>[CH:9]([C:11]1[CH:16]=[CH:15][C:14]([Si:5]([CH3:8])([CH3:7])[O:4][CH:1]([CH3:3])[CH3:2])=[CH:13][CH:12]=1)=[CH2:10]

参加物

反応条件

温度: 10 °C

実験手順

A solution of isopropoxydimethylchlorosilane (15.2 g, 100 mmole) in dry THF (50 mL) was added dropwise over a 1 hour period to a solution of (4-vinylphenyl)magnesium chloride, prepared from 4-vinylphenyl chloride (13.85 g, 100 mmole) and magnesium (3.0 g, 125 mmole) in dry 100 mL THF. The temperature was maintained at 10° C. during the addition. The reaction mixture was stirred at room temperature for over 18 hours. The desired product distilling at 45°-49° C./0.2 mm was obtained in 45% yield.

後処理

distillationThe desired product distilling at 45°-49° C./0.2 mm
customwas obtained in 45% yield

出典と根拠

ORDレコード: ord-03f27159cd4f48c8bc89eff936c386cd
出典データセット: uspto-grants-1994_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05278244

反応式

参加物

反応物 4

生成物 1

試薬・触媒・溶媒 1

反応条件

実験手順

後処理

出典と根拠

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