Triethoxychlorosilane → Chlorodifluoroacetic acid, triethoxysilyl ester

HRID 11983

反応式

HRID 11983 の反応式
[Cl:1][C:2]([F:7])([F:6])[C:3]([O-:5])=[O:4].[Na+].Cl[Si:10]([O:17][CH2:18][CH3:19])([O:14][CH2:15][CH3:16])[O:11][CH2:12][CH3:13]>CCOCC>[Cl:1][C:2]([F:7])([F:6])[C:3]([O:5][Si:10]([O:17][CH2:18][CH3:19])([O:14][CH2:15][CH3:16])[O:11][CH2:12][CH3:13])=[O:4]

参加物

4

反応物 2

HCID 78398TriethoxychlorosilaneHCID 2734985Sodium chlorodifluoroacetate

生成物 1

HCID 23523584Chlorodifluoroacetic acid, triethoxysilyl ester

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒2 回

反応条件

温度
-70 °C

実験手順

15.246 g (0.10 mol) sodium chlorodifluoroacetate, is dissolved to 100 mL Et2O and cooled to −70° C. 19.7 mL (0.10 mol, 19.872 g) chlorotriethoxysilane in Et2O (50 mL) was added dropwise to reaction solution. The solution was stirred for over night allowing it to warm up to room temperature. NaCl is removed by filtration and solution evaporated to dryness to result clear colourless liquid, chlorodifluoroacetic acid, triethoxysilyl ester.

後処理

  1. temperatureto warm up to room temperature
  2. customNaCl is removed by filtration and solution
  3. customevaporated to dryness

出典と根拠

ORDレコード
ord-f1b5569857ad4bc69f007d641c3d1aae
出典データセット
uspto-grants-2006_08
特許番号
US07098346B2

関連ノート

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