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Sodium borohydride → trans-3-[2-(7-Chloroquinolin-2-yl)ethenyl]benzyl alcohol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium borohydride | HCID 4311764 | — |
| 反応物 | 3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]benzaldehyde | HCID 10017305 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | trans-3-[2-(7-Chloroquinolin-2-yl)ethenyl]benzyl alcohol | HCID 10827738 | — |
反応手順
Solid sodium borohydride (2.5 g) was added in portions to a stirred suspension of crude 3-[2(E)-(7-chloroquinolin-2-yl)ethenyl]benzaldehyde (5.8 g) in methanol (200 ml). The mixture was filtered and the filtrate was concentrated to ca 70 ml and diluted with hot water to give crystals, m.p. 141° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05281593 |
| 出典データセット | uspto-grants-1994_01 |
| ORD ID | ord-79408cb9ec7d4ae1be7b3f1d54a7a93c |
| 出典メモ | uspto-grants-1994_01 |