反应详情

Solid sodium borohydride (2.5 g) was added in portions to a stirred suspension of crude 3-[2(E)-(7-chloroquinolin-2-yl)ethenyl]benzaldehyde (5.8 g) in methanol (200 ml). The mixture was filtered and the filtrate was concentrated to ca 70 ml and diluted with hot water to give crystals, m.p. 141° C.

1. filtrationThe mixture was filtered
2. concentrationthe filtrate was concentrated to ca 70 ml
3. additiondiluted with hot water
4. customto give crystals, m.p. 141° C.