(E)-3-(1H-Indol-7-yl)acrylonitrile → 3-(1H-Indol-7-YL)propanenitrile

HRID 1198536ノート

反応式

HRID 1198536 の反応式
[C:1](/[CH:3]=[CH:4]/[C:5]1[CH:6]=[CH:7][CH:8]=[C:9]2[C:13]=1[NH:12][CH:11]=[CH:10]2)#[N:2]>C(O)C.[Pd]>[C:1]([CH2:3][CH2:4][C:5]1[CH:6]=[CH:7][CH:8]=[C:9]2[C:13]=1[NH:12][CH:11]=[CH:10]2)#[N:2]

参加物

4

反応物 1

HCID 19959103(E)-3-(1H-Indol-7-yl)acrylonitrile

生成物 1

HCID 199591053-(1H-Indol-7-YL)propanenitrile

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

A solution of 7-[2-(E)-cyanoethenyl]indole (0.28 g) in ethanol (75 ml) was hydrogenated at 50 psi over 10% palladium on charcoal (0.1 g) for 4 hours. The catalyst was filtered off and the filtrate was evaporated to give the product.

後処理

  1. filtrationThe catalyst was filtered off
  2. customthe filtrate was evaporated
  3. customto give the product

出典と根拠

ORDレコード
ord-0f8edb9087e34736b4582c2d32ffe841
出典データセット
uspto-grants-1994_01
特許番号
US05281593

反応ノート

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