HCID 54361418、化合物 → 6-(4-Bromophenyl)-3-pyridineacetaldehyde
反応式
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([CH:14]=[CH:15][O:16]C)=[CH:10][N:9]=2)=[CH:4][CH:3]=1>O1CCCC1>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:13]=[CH:12][C:11]([CH2:14][CH:15]=[O:16])=[CH:10][N:9]=2)=[CH:6][CH:7]=1参加物
3
実験手順
A solution of 12.4 g of 2-(p-bromophenyl)-5-(2-methoxyvinyl)pyridine in 200 ml of tetrahydrofuran/2N hydrochloric acid (vol. 4:1) is heated to reflux for 1 hour while stirring. The reaction mixture is subsequently partitioned three times in diethyl ether/water. The organic extracts are washed twice with water, dried over magnesium sulphate, filtered and evaporated, whereby [2-(p-bromophenyl)-5-pyridyl]acetaldehyde is obtained as the residue.
後処理
- temperatureto reflux for 1 hour
- customThe reaction mixture is subsequently partitioned three times in diethyl ether/water
- washThe organic extracts are washed twice with water
- dry with materialdried over magnesium sulphate
- filtrationfiltered
- customevaporated
出典と根拠
- ORDレコード
- ord-89a686a0ad6643c780e49c34853a2e09
- 出典データセット
- uspto-grants-1990_02
- 特許番号
- US04898455
反応ノート
読み込み中…