Sodium Carbonate → 2-methoxy-6[(N-2-nitrophenyl)-amino]-8-methylquinoline

HRID 1198942ノート

反応式

HRID 1198942 の反応式
[CH3:1][O:2][C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[C:6]([CH3:14])[CH:7]=[C:8]([NH2:13])[CH:9]=2)[N:4]=1.F[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[N+:22]([O-:24])=[O:23].C(=O)([O-])[O-].[Na+].[Na+]>>[CH3:1][O:2][C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[C:6]([CH3:14])[CH:7]=[C:8]([NH:13][C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=3[N+:22]([O-:24])=[O:23])[CH:9]=2)[N:4]=1

参加物

4

反応物 3

HCID 10340Sodium CarbonateHCID 738951-Fluoro-2-nitrobenzeneHCID 198670716-Amino-2-methoxy-8-methylquinoline

生成物 1

HCID 198677162-methoxy-6[(N-2-nitrophenyl)-amino]-8-methylquinoline

実験手順

This compound, m.p. 185°, was prepared similarly to Preparation 20 using 2-methoxy-6-amino-8-methylquinoline, 1-fluoro-2-nitrobenzene, and sodium carbonate as starting materials. The product was characterised spectroscopically and used directly in Preparation 17 without further purification.

後処理

  1. customused directly in Preparation 17 without further purification

出典と根拠

ORDレコード
ord-39a85318e462431ca299a15576a8cc13
出典データセット
uspto-grants-1990_02
特許番号
US04898872

反応ノート

読み込み中…