m-Chloroperbenzoic acid → 4-Methyl-5-methylsulfinyl-3-(4-pyridyl)-4H-1,2,4-triazole
反応式
[CH3:1][N:2]1[C:6]([S:7][CH3:8])=[N:5][N:4]=[C:3]1[C:9]1[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=1.ClC1C=C(C=CC=1)C(OO)=[O:20]>C(Cl)Cl>[CH3:1][N:2]1[C:6]([S:7]([CH3:8])=[O:20])=[N:5][N:4]=[C:3]1[C:9]1[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=1参加物
4
実験手順
To a stirred, 0° C., solution of 4-methyl-5-methylthio-3-(4-pyridyl)-4H-1,2,4-triazole (4.54 g, 2.2×10-2 mole) and CH2Cl2 (125 ml) was added portionwise m-chloroperoxybenzoic acid (4.83 g, 2.24×10-2 mole, 80% active MCPBA). After stirring overnight the reaction was diluted with CH2Cl2 until homogeneous. The CH2Cl2 solution was then washed with saturated aqueous NaHCO3 and saturated aqueous NaCl. After drying over anhydrouse Na2SO4, the CH2Cl2 was evaporated at reduced pressure to give the desired product.
後処理
- washThe CH2Cl2 solution was then washed with saturated aqueous NaHCO3 and saturated aqueous NaCl
- dry with materialAfter drying over anhydrouse Na2SO4
- customthe CH2Cl2 was evaporated at reduced pressure
出典と根拠
- ORDレコード
- ord-c52e6f478925424aa6a7c7a858abebda
- 出典データセット
- uspto-grants-1990_02
- 特許番号
- US04900743
反応ノート
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