Sodium Hydroxide → HCID 178509268、化合物

HRID 1199484ノート

反応式

HRID 1199484 の反応式
C[N:2]([CH:4]=[C:5]([C:8](=[O:14])[C:9]1[O:10][CH:11]=[CH:12][CH:13]=1)[C:6]#[N:7])C.[N+:15]([O-])(O)=O.NNC(N)=N.[OH-].[Na+]>C(O)C>[NH2:2][C:4]1[C:5]([C:8]([C:9]2[O:10][CH:11]=[CH:12][CH:13]=2)=[O:14])=[CH:6][NH:7][N:15]=1

参加物

5

反応物 3

HCID 14798Sodium HydroxideHCID 515567863-(Dimethylamino)-2-(furan-2-carbonyl)acrylonitrileHCID 178513186HCID 178513186、化合物

生成物 1

HCID 178509268HCID 178509268、化合物収率 96.1%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A reaction mixture comprising 19.0 g of α-[(dimethylamino)methylene]-β-oxo-2-furanepropanenitrile, 16.1 g of aminoguanidine nitrate, 250 ml of ethanol and 11.0 ml of 10N sodium hydroxide was refluxed for 6 hours and then evaporated to dryness. Water was added to the crude residue and the precipitated solid was collected, giving 17.0 g of the desired product, mp 153°-155° C.

後処理

  1. customevaporated to dryness
  2. additionWater was added to the crude residue
  3. customthe precipitated solid was collected

出典と根拠

ORDレコード
ord-5130034f4d9b4ce89bad6b753046abb2
出典データセット
uspto-grants-1990_02
特許番号
US04900836

反応ノート

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