Methyl 2-bromo-4-fluoro-5-nitrophenoxyformate → HCID 14370869、化合物
反応式
[F:1][C:2]1[CH:7]=[C:6]([Br:8])[C:5]([O:9][C:10]([O:12][CH3:13])=[O:11])=[CH:4][C:3]=1[N+:14]([O-])=O.[H][H]>C(O)C.[Pt](=O)=O>[F:1][C:2]1[CH:7]=[C:6]([Br:8])[C:5]([O:9][C:10]([O:12][CH3:13])=[O:11])=[CH:4][C:3]=1[NH2:14]参加物
5
実験手順
Platinum dioxide (1.0 g) was added to a solution of 2-fluoro-4-bromo-5-methoxycarbonyloxinitrobenzene (30.4 g, 0.1 mol) in ethanol (300 ml) and the solution was stirred in normal atmospheric pressure of hydrogen until absorption of hydrogen was terminated. After completion of the reaction, the catalyst was removed by filtration and the solvent was removed by distillation from the filtrate to give a brown solid (28.0 g) of 2-fluoro-4-bromo-5-methoxycarbonyloxianiline.
後処理
- customwas terminated
- customAfter completion of the reaction
- customthe catalyst was removed by filtration
- customthe solvent was removed by distillation from the filtrate
出典と根拠
- ORDレコード
- ord-ea23dae610154e6cb766618876b7bfaf
- 出典データセット
- uspto-grants-1990_02
- 特許番号
- US04902337
反応ノート
読み込み中…