Pyridine → 3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-N-(2-hydroxy-ethoxy)-5-[(3-methylcarbamoyl-propoxyamino)-methyl]-benzamide
反応式
[BH3:44].[CH3:51][CH2:52][O:53][C:54](=[O:55])[CH3:56].[Cl:35][CH2:36][Cl:37].[F:1][c:2]1[c:3]([NH:26][c:27]2[c:28]([F:34])[cH:29][c:30]([I:33])[cH:31][cH:32]2)[c:4]([C:5](=[O:6])[NH:7][O:8][CH2:9][CH2:10][OH:11])[cH:12][c:13]([CH:16]=[N:17][O:18][CH2:19][CH2:20][CH2:21][C:22]([NH:23][CH3:24])=[O:25])[c:14]1[F:15].[OH:45][C:46]([CH:47]([Cl:48])[Cl:49])=[O:50].[n:38]1[cH:39][cH:40][cH:41][cH:42][cH:43]1>>[F:1][c:2]1[c:3]([NH:26][c:27]2[c:28]([F:34])[cH:29][c:30]([I:33])[cH:31][cH:32]2)[c:4]([C:5](=[O:6])[NH:7][O:8][CH2:9][CH2:10][OH:11])[cH:12][c:13]([CH2:16][NH:17][O:18][CH2:19][CH2:20][CH2:21][C:22]([NH:23][CH3:24])=[O:25])[c:14]1[F:15]
