Benzoyl Peroxide → 4,6-Dibromo-1,1-dimethyl-1,2,3,4-tetrahydronaphthalene
反応式
[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[C:8]([CH3:13])([CH3:12])[CH2:7][CH2:6][CH2:5]2.[Br:14]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[Br:14][CH:5]1[C:4]2[C:9](=[CH:10][CH:11]=[C:2]([Br:1])[CH:3]=2)[C:8]([CH3:13])([CH3:12])[CH2:7][CH2:6]1参加物
5
実験手順
To a solution of 1.2 g (5.0 mmol) of 6-bromo-1,2,3,4-tetrahydro-1,1-dimethylnaphthalene (Compound F) in 20 ml of CCl4 was added 0.97 g (5.5 mmol) of N-bromosuccinimide followed by 20 mg (0.08 mmol ) of benzoylperoxide. The mixture was refluxed for 3 hours, filtered and the filtrate washed with water (5 ml). The organic phase was dried over MgSO4 and then concentrated in vacuo to yield the title compound as a pale yellow oil.
後処理
- temperatureThe mixture was refluxed for 3 hours
- filtrationfiltered
- washthe filtrate washed with water (5 ml)
- dry with materialThe organic phase was dried over MgSO4
- concentrationconcentrated in vacuo
出典と根拠
- ORDレコード
- ord-d35af9b12f1b47e88a643494fdc123b8
- 出典データセット
- uspto-grants-1998_03
- 特許番号
- US05723620
反応ノート
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