Ammonia → 6-(5-Cyclopropylcarbamoyl-2-methyl-phenyl)-1-oxo-2-pyridin-4-ylmethyl-1,2-dihydro-isoquinoline-4-carboxylic acid piperidin-4-ylamide

反応式

[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([NH:14][C:15](=[O:16])[c:17]2[cH:18][n:19]([CH2:41][c:42]3[cH:43][cH:44][n:45][cH:46][cH:47]3)[c:20](=[O:40])[c:21]3[cH:22][cH:23][c:24](-[c:27]4[c:28]([CH3:39])[cH:29][cH:30][c:31]([C:33]([NH:34][CH:35]5[CH2:36][CH2:37]5)=[O:38])[cH:32]4)[cH:25][c:26]23)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:56][CH2:57][Cl:58].[NH3:55].[OH:48][C:49]([C:50]([F:51])([F:52])[F:53])=[O:54]>>[NH:8]1[CH2:9][CH2:10][CH:11]([NH:14][C:15](=[O:16])[c:17]2[cH:18][n:19]([CH2:41][c:42]3[cH:43][cH:44][n:45][cH:46][cH:47]3)[c:20](=[O:40])[c:21]3[cH:22][cH:23][c:24](-[c:27]4[c:28]([CH3:39])[cH:29][cH:30][c:31]([C:33]([NH:34][CH:35]5[CH2:36][CH2:37]5)=[O:38])[cH:32]4)[cH:25][c:26]23)[CH2:12][CH2:13]1