Tetrahydrofuran → 1-(5-tert-Butylisoxazol-3-yl)-3-(2-fluoro-4-(4-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)benzyl)piperazine-1-carbonyl)phenyl)urea

HRID 122263

反応式

[C:34]([CH3:35])([CH3:36])([CH3:37])[c:38]1[cH:39][c:40]([NH2:43])[n:41][o:42]1.[NH2:1][c:2]1[c:3]([F:33])[cH:4][c:5]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][N:13]([CH2:16][c:17]3[cH:18][cH:19][c:20]([C:23]([C:24]([F:25])([F:26])[F:27])([C:28]([F:29])([F:30])[F:31])[OH:32])[cH:21][cH:22]3)[CH2:14][CH2:15]2)[cH:6][cH:7]1.[O:44]1[CH2:45][CH2:48][CH2:47][CH2:46]1>>[NH:1]([c:2]1[c:3]([F:33])[cH:4][c:5]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][N:13]([CH2:16][c:17]3[cH:18][cH:19][c:20]([C:23]([C:24]([F:25])([F:26])[F:27])([C:28]([F:29])([F:30])[F:31])[OH:32])[cH:21][cH:22]3)[CH2:14][CH2:15]2)[cH:6][cH:7]1)[C:45]([NH:43][c:40]1[cH:39][c:38]([C:34]([CH3:35])([CH3:36])[CH3:37])[o:42][n:41]1)=[O:44]