Tetrahydrofuran → 3-(3-Chloro-thiophen-2-yl)-8-(1-ethyl-propyl)-2,6-dimethyl-imidazo[1,2-b]pyridazine

反応式

[Br:1][c:2]1[s:3][cH:4][cH:5][c:6]1[Cl:7].[CH2:13]([CH3:14])[CH:15]([CH2:16][CH3:17])[c:18]1[c:19]2[n:20]([n:21][c:22]([CH3:24])[cH:23]1)[c:25]([I:29])[c:26]([CH3:28])[n:27]2.[CH2:8]1[O:9][CH2:10][CH2:11][CH2:12]1.[Zn:30]>>[c:2]1(-[c:25]2[n:20]3[c:19]([c:18]([CH:15]([CH2:13][CH3:14])[CH2:16][CH3:17])[cH:23][c:22]([CH3:24])[n:21]3)[n:27][c:26]2[CH3:28])[s:3][cH:4][cH:5][c:6]1[Cl:7]