Dichloromethane → 3-Amino-5-benzoyl-1-methyl-3,4-dihydro-1,5-benzodiazepin-2-one

反応式

[C:1]([O:2][C:3](=[O:4])[NH:7][CH:8]1[CH2:9][N:10]([C:21]([c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)=[O:28])[c:11]2[c:12]([cH:17][cH:18][cH:19][cH:20]2)[N:13]([CH3:16])[C:14]1=[O:15])([CH3:5])([CH3:6])[CH3:29].[Cl:37][CH2:38][Cl:39].[OH:30][C:31]([C:32]([F:33])([F:34])[F:35])=[O:36]>>[NH2:7][CH:8]1[CH2:9][N:10]([C:21]([c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)=[O:28])[c:11]2[c:12]([cH:17][cH:18][cH:19][cH:20]2)[N:13]([CH3:16])[C:14]1=[O:15]

参加物

反応物 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 69284319tert-butyl N-(5-benzoyl-1-methyl-2-oxo-3,4-dihydro-1,5-benzodiazepin-3-yl)carbamate

生成物 1

HCID 210765923-Amino-5-benzoyl-1-methyl-3,4-dihydro-1,5-benzodiazepin-2-one

出典と根拠

ORDレコード: ord-8e07a158588e49dea0633abc5668cb39
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…