Chloride → (2RS,5SR)-5-(4-Fluoro-phenyl)-1-(toluene-4-sulfonyl)-pyrrolidine-2-carbonitrile

反応式

[C:35]([O:36][CH2:37][CH3:38])(=[O:39])[CH3:40].[CH3:29][CH2:30][CH2:31][CH2:32][CH2:33][CH3:34].[Cl-:26].[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH2:9][CH2:10][CH:11]([C:23](=[O:24])[NH2:25])[N:12]2[S:13](=[O:14])(=[O:15])[c:16]2[cH:17][cH:18][c:19]([CH3:22])[cH:20][cH:21]2)[cH:6][cH:7]1.[P+:27]=[O:28]>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH2:9][CH2:10][CH:11]([C:23]#[N:25])[N:12]2[S:13](=[O:14])(=[O:15])[c:16]2[cH:17][cH:18][c:19]([CH3:22])[cH:20][cH:21]2)[cH:6][cH:7]1