Trifluoroacetic acid → N2-(3-chlorophenyl)-N4-piperidin-2-ylmethyl-pyrimidine-2,4-diamine

反応式

[C:1]([O:2][C:3](=[O:4])[N:8]1[CH:9]([CH2:14][NH:15][c:16]2[n:17][c:18]([NH:22][c:23]3[cH:24][c:25]([Cl:29])[cH:26][cH:27][cH:28]3)[n:19][cH:20][cH:21]2)[CH2:10][CH2:11][CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[OH:30][C:31]([C:32]([F:33])([F:34])[F:35])=[O:36]>>[NH:8]1[CH:9]([CH2:14][NH:15][c:16]2[n:17][c:18]([NH:22][c:23]3[cH:24][c:25]([Cl:29])[cH:26][cH:27][cH:28]3)[n:19][cH:20][cH:21]2)[CH2:10][CH2:11][CH2:12][CH2:13]1

参加物

反応物 2

HCID 6422Trifluoroacetic acid

HCID 578613172-{[2-(3-Chlorophenylamino)pyrimidin-4-ylamino]methyl}-piperidine-1-carboxylic acid tert-butyl ester

生成物 1

HCID 24797612N2-(3-chlorophenyl)-N4-piperidin-2-ylmethyl-pyrimidine-2,4-diamine

出典と根拠

ORDレコード: ord-25fdf0c59b4b4e0888cb45f97b3bb43c
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…