Triphenylphosphine → 4-Fluorophenethyltriphenylphosphonium bromide

HRID 12369

反応式

HRID 12369 の反応式
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][Br:10])=[CH:4][CH:3]=1.[C:11]1([P:17]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>C1(C)C=CC=CC=1>[Br-:10].[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][P+:17]([C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 11776TriphenylphosphineHCID 5731534-Fluorophenethyl bromide

生成物 1

HCID 223867454-Fluorophenethyltriphenylphosphonium bromide

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

反応条件

温度
200 °C

実験手順

4-Fluorophenylethyl bromide (700 mg, 3.44 mmol) was dissolved in toluene (4 mL), triphenylphosphine (904 mg, 3.44 mmol) added and the solution heated for 10 min in a sealed flask at 200° C. under microwave heating. After cooling to rt, the solvent was decanted and the title compound was obtained quantitatively as the remaining glassy solid, which was used without further purification.

後処理

  1. temperatureheating
  2. temperatureAfter cooling to rt
  3. customthe solvent was decanted

出典と根拠

ORDレコード
ord-ced818104f6646a0b4c67d321a5aa17e
出典データセット
uspto-grants-2010_06
特許番号
US07727999B2

関連ノート

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