Tetrahydrofuran → 3-Fluoro-4-[(1,2,4-thiadiazol-5-ylamino)sulfonyl]benzoic acid

反応式

[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[CH3:19][Si:20]([N-:21][Si:22]([CH3:23])([CH3:24])[CH3:25])([CH3:26])[CH3:27].[CH3:1][O:2][c:3]1[cH:4][c:5]([O:12][CH3:13])[cH:14][cH:15][c:16]1[CH2:17][NH:6][c:7]1[n:8][cH:9][n:10][s:11]1.[Cl:28][S:29](=[O:30])(=[O:31])[c:32]1[c:33]([F:41])[cH:34][c:35]([C:36](=[O:37])[OH:38])[cH:39][cH:40]1.[Li+:18]>>[NH:6]([c:7]1[n:8][cH:9][n:10][s:11]1)[S:29](=[O:30])(=[O:31])[c:32]1[c:33]([F:41])[cH:34][c:35]([C:36](=[O:37])[OH:38])[cH:39][cH:40]1