Sodium Hydroxide → 5-Fluoro-2,4-dinitrophenol
反応式
[F:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([N+:11]([O-:13])=[O:12])=[C:4](F)[CH:3]=1.[OH-:15].[Na+]>O>[F:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([N+:11]([O-:13])=[O:12])=[C:4]([OH:15])[CH:3]=1参加物
4
実験手順
0.41 g of 1,3-difluoro-4,6-dinitrobenzene was dissolved in 8 ml of 0.5 N aqueous sodium hydroxide solution and refluxed for 2 hours. After cooling, it was diluted with water and extracted three times with diethyl ether. The aqueous phase was made acidic by adding 1N hydrochloric acid and extracted with diethyl ether. The organic phase was dried on sodium sulfate and concentrated by evaporation in a vacuum.
後処理
- temperaturerefluxed for 2 hours
- temperatureAfter cooling
- extractionextracted three times with diethyl ether
- additionby adding 1N hydrochloric acid
- extractionextracted with diethyl ether
- customThe organic phase was dried on sodium sulfate
- concentrationconcentrated by evaporation in a vacuum
出典と根拠
- ORDレコード
- ord-48b5eafb6e3345a3b5a002190c08fae3
- 出典データセット
- uspto-grants-2006_10
- 特許番号
- US07115645B2
反応ノート
読み込み中…