2-(3-Methoxy-prop-1-ynyl)-phenoxy-acetic acid ethyl ester → HCID 67072081、化合物

HRID 1242278ノート

反応式

HRID 1242278 の反応式
[CH2:1]([O:3][C:4](=[O:18])[CH2:5][O:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[C:13]#[C:14][CH2:15][O:16][CH3:17])[CH3:2]>CCOC(C)=O.[Pd]>[CH2:1]([O:3][C:4](=[O:18])[CH2:5][O:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[CH2:13][CH2:14][CH2:15][O:16][CH3:17])[CH3:2]

参加物

4

反応物 1

HCID 670722722-(3-Methoxy-prop-1-ynyl)-phenoxy-acetic acid ethyl ester

生成物 1

HCID 67072081HCID 67072081、化合物

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 8857Ethyl Acetate溶媒

実験手順

9.54 g (38.4 mmol) of the above prepared [2-(3-methoxy-prop-1-ynyl)-phenoxy]-acetic acid ethyl ester was hydrogenated at RT in 130 ml of AcOEt over 2.39 g of Pd/C (10%) under 1 atm of H2-pressure. After 2 h at ambient temperature, the reaction mixture was filtrated over Celite and carefully rinsed with AcOEt. Evaporation of the solvent left finally 9.39 g of the title compound as colorless oil.

後処理

  1. filtrationthe reaction mixture was filtrated over Celite
  2. washcarefully rinsed with AcOEt
  3. customEvaporation of the solvent
  4. waitleft finally 9.39 g of the title compound as colorless oil

出典と根拠

ORDレコード
ord-357df83964494af6a97e52c9a03907cc
出典データセット
uspto-grants-2006_10
特許番号
US07115611B2

反応ノート

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