N,N,N',N'-Tetramethylazodicarboxamide → HCID 86597822、化合物
反応式
[CH2:1]([O:3][C:4](=[O:17])[C:5]([O:8][C:9]1[CH:14]=[CH:13][C:12]([OH:15])=[CH:11][C:10]=1[CH3:16])([CH3:7])[CH3:6])[CH3:2].[F:18][C:19]([F:40])([F:39])[O:20][C:21]1[CH:26]=[CH:25][C:24]([C:27]2[N:32]=[CH:31][C:30]([CH2:33]O)=[C:29]([C:35]([F:38])([F:37])[F:36])[CH:28]=2)=[CH:23][CH:22]=1.CN(C)C(N=NC(N(C)C)=O)=O.C(P(CCCC)CCCC)CCC>>[CH2:1]([O:3][C:4](=[O:17])[C:5]([CH3:6])([O:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:33][C:30]2[CH:31]=[N:32][C:27]([C:24]3[CH:23]=[CH:22][C:21]([O:20][C:19]([F:39])([F:18])[F:40])=[CH:26][CH:25]=3)=[CH:28][C:29]=2[C:35]([F:38])([F:36])[F:37])=[CH:11][C:10]=1[CH3:16])[CH3:7])[CH3:2]参加物
5
実験手順
In analogy to the procedure described in example 43E], 2-(4-hydroxy-2-methyl-phenoxy)-2-methyl-propionic acid ethyl ester (described in WO 02/092590) was reacted with [6-(4-trifluoromethoxy-phenyl)-4-trifluoromethyl-pyridin-3-yl]-methanol in the presence of N,N,N′,N′-tetramethylazodicarboxamide and tributylphosphine to give the title compound as colorless oil.