Acetonitrile → 7-[1-(t-Butoxycarbonylamino)-3-azabicyclo[3.2.0]hept-3-yl]-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid

反応式

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][C:9]12[CH2:10][NH:11][CH2:12][CH:13]1[CH2:14][CH2:15]2.[CH3:36][C:37]#[N:38].[Cl:16][c:17]1[c:18]([F:35])[c:19]([F:34])[cH:20][c:21]2[c:22](=[O:33])[c:23]([C:30](=[O:31])[OH:32])[cH:24][n:25]([CH:27]3[CH2:28][CH2:29]3)[c:26]12>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][C:9]12[CH2:10][N:11]([c:18]3[c:17]([Cl:16])[c:26]4[c:21]([cH:20][c:19]3[F:34])[c:22](=[O:33])[c:23]([C:30](=[O:31])[OH:32])[cH:24][n:25]4[CH:27]3[CH2:28][CH2:29]3)[CH2:12][CH:13]1[CH2:14][CH2:15]2