N,N-dibutyl-4-nitroaniline → HCID 11680158、化合物
反応式
[N+:1]([C:4]1[CH:18]=[CH:17][C:7]([N:8]([CH2:13][CH2:14][CH2:15][CH3:16])[CH2:9][CH2:10][CH2:11][CH3:12])=[CH:6][CH:5]=1)([O-])=O>CO.[Pd]>[CH2:9]([N:8]([CH2:13][CH2:14][CH2:15][CH3:16])[C:7]1[CH:6]=[CH:5][C:4]([NH2:1])=[CH:18][CH:17]=1)[CH2:10][CH2:11][CH3:12]参加物
4
実験手順
To a solution of 4-nitro-N,N-dibutylaniline from Example 40A (1.0 g, 4.0 mmol) in methanol (10 ml) was added palladium 10 wt % on activated carbon (85 mg, 0.08 mmol) under an atmosphere of hydrogen. The reaction mixture was stirred at room temperature for 4 hours and filtered through celite. After solvent were removed under reduced pressure, the titled material was obtained as a white solid, which was used in next step without purification.
後処理
- filtrationfiltered through celite
- customAfter solvent were removed under reduced pressure
出典と根拠
- ORDレコード
- ord-85d189a85359411399ed03b60f7a19f3
- 出典データセット
- uspto-grants-2006_10
- 特許番号
- US07115767B2
反応ノート
読み込み中…