Sodium hydride → 3-{3-[4-(2-Methyl-quinolin-4-ylmethoxy)-phenyl]-4,5-dihydro-isoxazol-5-yl}-acrylic acid tert-butyl ester

反応式

COP([CH2:7][C:8]([O:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[O:9])(OC)=O.[H-].[Na+].[CH3:17][C:18]1[CH:27]=[C:26]([CH2:28][O:29][C:30]2[CH:35]=[CH:34][C:33]([C:36]3[CH2:40][CH:39]([CH:41]=O)[O:38][N:37]=3)=[CH:32][CH:31]=2)[C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[N:19]=1>CN(C=O)C>[C:11]([O:10][C:8](=[O:9])[CH:7]=[CH:41][CH:39]1[O:38][N:37]=[C:36]([C:33]2[CH:34]=[CH:35][C:30]([O:29][CH2:28][C:26]3[C:25]4[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=4)[N:19]=[C:18]([CH3:17])[CH:27]=3)=[CH:31][CH:32]=2)[CH2:40]1)([CH3:12])([CH3:13])[CH3:14]