Sulfuric Acid → 1H-Pyrazole, 4,5-diamine-1-methyl-, sulfate (1:1)

HRID 1247771

反応式

HRID 1247771 の反応式
[NH2:1][C:2]1[N:6]([CH3:7])[N:5]=[CH:4][C:3]=1[N:8]=O.[S:10](=[O:14])(=[O:13])([OH:12])[OH:11]>O.[Pd]>[S:10](=[O:12])(=[O:11])([OH:14])[OH:13].[NH2:8][C:3]1[CH:4]=[N:5][N:6]([CH3:7])[C:2]=1[NH2:1]

参加物

5

反応物 2

HCID 1118Sulfuric AcidHCID 128515805-Amino-1-methyl-4-nitrosopyrazole

生成物 1

HCID 219045711H-Pyrazole, 4,5-diamine-1-methyl-, sulfate (1:1)

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 962Water溶媒

実験手順

To a solution of 5-amino-1-methyl-4-nitrosopyrazole (1 g) in water (40 ml) were added concentrated sulfuric acid (0.423 ml) and palladium on carbon (0.3 g) under a hydrogen atmosphere. The mixture was stirred overnight. The reaction mixture was filtered, and the filtrate was evaporated in vacuo. To the residue was added isopropyl alcohol, and the resulting precipitate was collected by filtration to give 4,5-diamino-1-methylpyrazole sulfuric acid salt (1.71 g).

後処理

  1. filtrationThe reaction mixture was filtered
  2. customthe filtrate was evaporated in vacuo
  3. additionTo the residue was added isopropyl alcohol
  4. filtrationthe resulting precipitate was collected by filtration

出典と根拠

ORDレコード
ord-d95b855a751240af91eca2fb50ef3e16
出典データセット
uspto-grants-2006_10
特許番号
US07129232B2

関連ノート

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