L-Phenylalanine → L-Phenylalanine

HRID 1248107

反応式

HRID 1248107 の反応式
[NH2:1][C@H:2]([C:10]([OH:12])=[O:11])[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.C1C=[C:17]2C([C:21]([OH:25])([OH:24])[C:22](=O)[C:16]2=[CH:15]C=1)=O>Cl>[NH2:1][C@H:2]([C:10]([OH:12])=[O:11])[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[CH3:2][NH:1][C@H:22]([C:21]([OH:25])=[O:24])[CH:16]([CH3:17])[CH3:15]

参加物

5

反応物 2

HCID 6140L-PhenylalanineHCID 10236Ninhydrin

生成物 2

HCID 6140L-PhenylalanineHCID 444080N-Methyl-L-valine

試薬・触媒・溶媒 1

HCID 313Hydrochloric Acid溶媒2 回

実験手順

Constituent amino acids: K-4 is hydrolyzed in 6N hydrochloric acid at 110° C. for 20 hours and the resulting mixture is analyzed by an amino acid automatic analyzer, whereby phenylalanine and an unidentified ninhydrin reaction-positive substance are detected. Separately, a solution of K-4 in 20% hydrochloric acid is stirred at 110° C. for 21 hours and then concentrated under reduced pressure. The residue is chromatographed on a column of silica gel (developing solvent: n-butanol:acetic acid:water=4:1:1) to give phenylalanine, N-methylvaline and the aforesaid ninhydrin reaction-positive substance.

後処理

  1. concentrationconcentrated under reduced pressure
  2. customThe residue is chromatographed on a column of silica gel (developing solvent: n-butanol:acetic acid:water=4:1:1)

出典と根拠

ORDレコード
ord-6d7074871f354b5990c169816f3b9d79
出典データセット
uspto-grants-1985_06
特許番号
US04522812

関連ノート

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