化工社化工社 化学情報印刷レポート · 研究参考用
Hydrazine hydrate (1:1) → 3,3a,4,5,6,7-hexahydro-2H-indazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 反応物 | 2-((Dimethylamino)methyl)cyclohexanone | HCID 85838 | — |
| 溶媒 | 1-Butanol | HCID 263 | — |
| 生成物 | 3,3a,4,5,6,7-hexahydro-2H-indazole | HCID 59339338 | — |
反応手順
Hydrazine hydrate (28.0 mL) was dissolved in n-BuOH (200 mL) and cooled in an ice bath. A solution of 2-dimethylaminomethyl-cyclohexanone (64.0 g) in n-BuOH (50 mL) was added dropwise, the mixture was slowly warmed and refluxed for 20 hours. The solvent was evaporated under reduced pressure.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07728018B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-d60c876a3fb140c791fbe1953581d169 |
| 出典メモ | uspto-grants-2010_06 |