p-[4-[2-(p-Pentylphenyl)vinyl]cyclohexyl]benzonitrile → HCID 178442124、化合物

反応式

[CH2:1]([C:6]1[CH:11]=[CH:10][C:9]([CH:12]=[CH:13][CH:14]2[CH2:19][CH2:18][CH:17]([C:20]3[CH:27]=[CH:26][C:23]([C:24]#[N:25])=[CH:22][CH:21]=3)[CH2:16][CH2:15]2)=[CH:8][CH:7]=1)[CH2:2][CH2:3][CH2:4][CH3:5].[H][H]>C1(C)C=CC=CC=1.[Pd]>[CH2:1]([C:6]1[CH:11]=[CH:10][C:9]([CH2:12][CH2:13][C@H:14]2[CH2:19][CH2:18][C@H:17]([C:20]3[CH:21]=[CH:22][C:23]([C:24]#[N:25])=[CH:26][CH:27]=3)[CH2:16][CH2:15]2)=[CH:8][CH:7]=1)[CH2:2][CH2:3][CH2:4][CH3:5]

参加物

実験手順

7.0 g of p-[4-[2-(p-pentylphenyl)vinyl]cyclohexyl]benzonitrile were dissolved in 350 ml of toluene, treated with 1.4 g of palladium/carbon (10%) and hydrogenated at room temperature and normal pressure until the hydrogen uptake came to a standstill. The crude p-[trans-4-[2-(p-pentylphenyl)ethyl]cyclohexyl]benzonitrile obtained after filtering off the catalyst and concentrating the filtrate was recrystallized twice from ethanol. Yield 4.2 g; m.p. (C--N) 61.5° C., cl.p. (N--I) 126° C.