Hydrogen Bromide → 5-(4-Aminophenyl)-3-methyl-2(1H)-pyrazinone hydrobromide
反応式
C(OC([NH:11][C:12]1[CH:17]=[CH:16][C:15]([C:18]2[N:19]=[C:20]([CH3:25])[C:21](=[O:24])[NH:22][CH:23]=2)=[CH:14][CH:13]=1)=O)C1C=CC=CC=1.[BrH:26]>C(O)(=O)C>[BrH:26].[NH2:11][C:12]1[CH:13]=[CH:14][C:15]([C:18]2[N:19]=[C:20]([CH3:25])[C:21](=[O:24])[NH:22][CH:23]=2)=[CH:16][CH:17]=1参加物
4
実験手順
5-(4-Benzyloxycarbonylaminophenyl)-3-methyl-2(1H)-pyrazinone (1.5 g) was treated with hydrogen bromide in acetic acid in a manner similar to that described in Description 3 to give the title compound as its hydrobromide salt (1.09 g) which on recrystallisation from ethanol/ether had m.p.>300° C.; ν(Nujol mull) 1632, 1640 cm-1.
出典と根拠
- ORDレコード
- ord-0dc7bb33f5c04acaa483a0776448cb55
- 出典データセット
- uspto-grants-1986_12
- 特許番号
- US04632924
反応ノート
読み込み中…