Tetrahydrofuran → N-(3-(2-(2-Chloropyrimidin-4-yl)acetyl)-2-fluorophenyl)-2,5-difluorobenzenesulfonamide

HRID 124982

反応式

[CH2:48]1[O:49][CH2:50][CH2:51][CH2:52]1.[CH3:25][Si:26]([N-:27][Si:28]([CH3:29])([CH3:30])[CH3:31])([CH3:32])[CH3:33].[CH3:42][CH2:43][O:44][C:45]([CH3:46])=[O:47].[Cl:34][c:35]1[n:36][cH:37][cH:38][c:39]([CH3:41])[n:40]1.[F:1][c:2]1[c:3]([S:9](=[O:10])(=[O:11])[NH:12][c:13]2[c:14]([F:23])[c:15]([C:16]([O:18][CH3:17])=[O:19])[cH:20][cH:21][cH:22]2)[cH:4][c:5]([F:8])[cH:6][cH:7]1.[Li+:24]>>[F:1][c:2]1[c:3]([S:9](=[O:10])(=[O:11])[NH:12][c:13]2[c:14]([F:23])[c:15]([C:16](=[O:18])[CH2:41][c:39]3[cH:38][cH:37][n:36][c:35]([Cl:34])[n:40]3)[cH:20][cH:21][cH:22]2)[cH:4][c:5]([F:8])[cH:6][cH:7]1