Ethanolamine → HCID 14209234、化合物

HRID 1252397ノート

反応式

HRID 1252397 の反応式
[Br:1][C:2]1[CH:3]=[N:4][C:5]2[C:10]([C:11]=1Cl)=[CH:9][CH:8]=[CH:7][CH:6]=2.[CH2:13]([CH2:15][NH2:16])[OH:14]>O>[Br:1][C:2]1[CH:3]=[N:4][C:5]2[C:10]([C:11]=1[NH:16][CH2:15][CH2:13][OH:14])=[CH:9][CH:8]=[CH:7][CH:6]=2

参加物

4

反応物 2

HCID 700EthanolamineHCID 6183063-Bromo-4-chloroquinoline

生成物 1

HCID 14209234HCID 14209234、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

反応条件

温度
150 °C

実験手順

A mixture of 9.1 g of 3-bromo-4-chloro-quinoline and 2.0 g of ethanolamine was heated at 150° C. for 30 minutes. The reaction mixture was cooled, 60 ml of water was added and the precipitate was collected by filtration and recrystallized from isopropanol. The yield was 9.5 g, mp 163°-165° C.

後処理

  1. temperatureThe reaction mixture was cooled
  2. filtrationthe precipitate was collected by filtration
  3. customrecrystallized from isopropanol

出典と根拠

ORDレコード
ord-3b0008b4baf14a619161af1e78ef9f03
出典データセット
uspto-grants-1988_05
特許番号
US04743601

反応ノート

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