Oxalyl chloride → 2-(5-t-Butylfuran-2-yl)-cyclopropanecarbonyl chloride
反応式
[C:1]([C:5]1[O:9][C:8]([CH:10]2[CH2:12][CH:11]2[C:13]([OH:15])=O)=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].C(Cl)(=O)C([Cl:19])=O>CCCCCC>[C:1]([C:5]1[O:9][C:8]([CH:10]2[CH2:12][CH:11]2[C:13]([Cl:19])=[O:15])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2]参加物
4
実験手順
A mixture of 2-(5-t-butylfuran-2-yl)-cyclopropanecarboxylic acid (3.6 g, 0.017 mol) and oxalyl chloride (4.4 g, 0.035 mol) in hexane (40 ml) was stirred at room temperature for 2 hours and then warmed at 60° C. for 3 hours. The hexane and excess oxalyl chloride were removed in vacuo to give 2-(5-t-butylfuran-2-yl)-cyclopropanecarbonyl chloride (3.9 g, 100%) as a pale yellow liquid which was used in the next stage without further purification.
後処理
- temperaturewarmed at 60° C. for 3 hours
- customThe hexane and excess oxalyl chloride were removed in vacuo
出典と根拠
- ORDレコード
- ord-d08a45b09c16472e88b16f654b30e951
- 出典データセット
- uspto-grants-1988_05
- 特許番号
- US04743602
反応ノート
読み込み中…