Methyl isothiocyanate → HCID 54138282、化合物
反応式
[NH2:1][C:2]1[CH:6]=[N:5][N:4]([CH2:7][CH2:8][CH2:9][CH2:10][C:11]#[N:12])[N:3]=1.[CH3:13][N:14]=[C:15]=[S:16]>C(#N)C>[CH3:13][NH:14][C:15](=[S:16])[NH:1][C:2]1[CH:6]=[N:5][N:4]([CH2:7][CH2:8][CH2:9][CH2:10][C:11]#[N:12])[N:3]=1参加物
4
実験手順
A solution of 5-(4-amino-1,2,3-triazol-2-yl)valeronitrile (1.65 g.) in acetonitrile (5 ml.) and methylisothiocyanate (0.73 g.) was stirred for 18 hours at ambient temperature and then heated under reflux for 6 hours. The solvent was evaporated and the residue was triturated with ether/EtOH to give 5-[4-(3-methylthioureido)-1,2,3-triazol-2-yl]valeronitrile as a white solid.
後処理
- temperatureheated
- temperatureunder reflux for 6 hours
- customThe solvent was evaporated
- customthe residue was triturated with ether/EtOH
出典と根拠
- ORDレコード
- ord-16827c2fdad849ca88fc7c58c4ded27d
- 出典データセット
- uspto-grants-1988_05
- 特許番号
- US04748165
反応ノート
読み込み中…