Acetohydrazide → HCID 178485101、化合物
反応式
[CH3:1][N:2]=[C:3]([NH2:18])[NH:4][C:5]1[CH:9]=[N:8][N:7]([CH2:10][CH2:11][CH2:12][CH2:13][C:14](=[NH:17])OC)[N:6]=1.[C:19]([NH:22][NH2:23])(=[O:21])[CH3:20]>CO>[C:19]([NH:22][NH:23][C:14](=[NH:17])[CH2:13][CH2:12][CH2:11][CH2:10][N:7]1[N:6]=[C:5]([NH:4][C:3]([NH2:18])=[N:2][CH3:1])[CH:9]=[N:8]1)(=[O:21])[CH3:20]参加物
4
実験手順
Methyl 5-[4-[2-methylguanidino)-1,2,3-triazol2-yl]valerimidate (1.0 g.) in MeOH (12 ml.) was treated with acethydrazide (0.22 g.) and the solution stirred for 18 nours. Evaporation of the solvent and trituration of the resioue with ether/EtOH gave N-acetylamino-5[4-(2-methylguanidino)-1,2,3-triazol-2-yl]valeramidine as a yellow sticky solid [0.54 g.) which was used without further purification.
後処理
- customEvaporation of the solvent and trituration of the resioue with ether/EtOH
出典と根拠
- ORDレコード
- ord-ad5cbedd866444acaf8289d46b677549
- 出典データセット
- uspto-grants-1988_05
- 特許番号
- US04748165
反応ノート
読み込み中…