Dimethyl Sulfoxide → p-Methylcinnamaldehyde

HRID 12534

反応式

HRID 12534 の反応式
C(Cl)(=O)C(Cl)=O.CS(C)=O.[CH3:11][C:12]1[CH:17]=[CH:16][C:15](/[CH:18]=[CH:19]/[CH2:20][OH:21])=[CH:14][CH:13]=1.C(N(CC)CC)C>C(Cl)Cl>[CH3:11][C:12]1[CH:17]=[CH:16][C:15](/[CH:18]=[CH:19]/[CH:20]=[O:21])=[CH:14][CH:13]=1

参加物

6

反応物 4

HCID 679Dimethyl SulfoxideHCID 8471TriethylamineHCID 65578Oxalyl chlorideHCID 53874824-Methylcinnamyl alcohol2 回

生成物 1

HCID 5371802p-Methylcinnamaldehyde

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

Following General Procedure H, oxalyl chloride (7.1 ml, 14.2 mmol, 2 M in CH2Cl2), DMSO (1.3 ml, 18.9 mmol), (E)-3-(4-methylphenyl)prop-2-en-1-ol (Compound 41, 1.4 g, 9.5 mmol) and triethylamine (4.4 ml, 31.4 mmol) in CH2Cl2 (5 ml) were reacted to obtain the title compound as an oil.

後処理

  1. customwere reacted

出典と根拠

ORDレコード
ord-ff46d30221ab41f09c751f2de95c3f11
出典データセット
uspto-grants-2010_06
特許番号
US07728014B2

関連ノート

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