2-Pyrazinecarboxylic acid → N-[5-[2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]pyrazine-2-carboxamide

HRID 125471

反応式

[CH3:66][CH2:67][O:68][C:69]([CH3:70])=[O:71].[CH:57]([N:58]([CH2:59][CH3:60])[CH:61]([CH3:62])[CH3:63])([CH3:64])[CH3:65].[F:1][c:2]1[c:3]([CH:9]2[N:10]([c:14]3[n:15][c:16]4[n:17]([cH:18][cH:19]3)[n:20][cH:21][c:22]4[NH2:23])[CH2:11][CH2:12][CH2:13]2)[cH:4][c:5]([F:8])[cH:6][cH:7]1.[O:72]=[CH:73][N:74]([CH3:75])[CH3:76].[P-:33]([F:34])([F:35])([F:36])([F:37])([F:38])[F:39].[n:24]1[c:25]([C:30](=[O:31])[OH:32])[cH:26][n:27][cH:28][cH:29]1.[n:40]1([O:41][C:42]([N:43]([CH3:44])[CH3:45])=[N+:46]([CH3:47])[CH3:48])[c:49]2[n:50][cH:51][cH:52][cH:53][c:54]2[n:55][n:56]1>>[F:1][c:2]1[c:3]([CH:9]2[N:10]([c:14]3[n:15][c:16]4[n:17]([cH:18][cH:19]3)[n:20][cH:21][c:22]4[NH:23][C:30]([c:25]3[n:24][cH:29][cH:28][n:27][cH:26]3)=[O:31])[CH2:11][CH2:12][CH2:13]2)[cH:4][c:5]([F:8])[cH:6][cH:7]1