Dimethyl Sulfoxide → 4-Isopropylcinnamaldehyde

HRID 12573

反応式

HRID 12573 の反応式
C(Cl)(=O)C(Cl)=O.CS(C)=O.[CH:11]([C:14]1[CH:19]=[CH:18][C:17](/[CH:20]=[CH:21]/[CH2:22][OH:23])=[CH:16][CH:15]=1)([CH3:13])[CH3:12].C(N(CC)CC)C>C(Cl)Cl>[CH:11]([C:14]1[CH:15]=[CH:16][C:17](/[CH:20]=[CH:21]/[CH:22]=[O:23])=[CH:18][CH:19]=1)([CH3:13])[CH3:12]

参加物

6

反応物 4

HCID 679Dimethyl SulfoxideHCID 8471TriethylamineHCID 65578Oxalyl chlorideHCID 21961314(2E)-3-[4-(Propan-2-yl)phenyl]prop-2-en-1-ol2 回

生成物 1

HCID 53548974-Isopropylcinnamaldehyde

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

Following General Procedure H, oxalyl chloride (9.5 ml, 19.0 mmol, 2M in CH2Cl2), DMSO (1.8 ml, 25.3 mmol), (E)-3-(4-isopropylphenyl)prop-2-en-1-ol (Compound 109, 2.2 g, 12.6 mmol) and triethylamine (7.1 ml, 50.7 mmol) in CH2Cl2 (100 ml) were reacted to obtain the title compound as an oil.

後処理

  1. customwere reacted

出典と根拠

ORDレコード
ord-91fe98f3a159420ea2965d62c2c78fad
出典データセット
uspto-grants-2010_06
特許番号
US07728014B2

関連ノート

読み込み中…