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Methallyl alcohol → 4-(2-Methyl-allyloxymethyl)benzoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methallyl alcohol | HCID 10557 | — |
| 反応物 | 4-(Bromomethyl)benzoic acid | HCID 22599 | — |
| 反応物 | Sodium hydride | HCID 24758 | — |
| 反応物 | 4-But-3-enyloxymethyl-benzoic acid | HCID 22136996 | — |
| 生成物 | 4-(2-Methyl-allyloxymethyl)benzoic acid | HCID 25056517 | — |
反応手順
The reaction of 2-Methyl-prop-2-en-1-ol and 4-Bromomethyl-benzoic acid in the presence of sodium hydride was performed as described for Compound 33 to give 4-(2-Methyl-allyloxymethyl)benzoic acid as white powder. 1H-NMR (400 MHz, d6-DMSO): 12.85 (S, COOH); 7.91 (d, J=8.3, 2 arom. H); 7.42 (d, J=8.3, 2 arom.H); 4.96, 4.88 (2 s-like; C═CH2); 4.51 (s, —OCH2—C6H4); 3.90 (s, CH2O); 1.69 (s, CH3). 13C-NMR (100 MHz, d6-DMSO): 167.12 (—C═O); 143.60; 141.98; 129.74; 129.32 (2 arom.C); 127.09 (2 arom.C); 111.74; 73.50; 70.52; 19.29.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08466199B2 |
| 出典データセット | uspto-grants-2013_06 |
| ORD ID | ord-1ffdd83029574df5b980b582d2fa0106 |
| 出典メモ | uspto-grants-2013_06 |