反应详情

The reaction of 2-Methyl-prop-2-en-1-ol and 4-Bromomethyl-benzoic acid in the presence of sodium hydride was performed as described for Compound 33 to give 4-(2-Methyl-allyloxymethyl)benzoic acid as white powder. 1H-NMR (400 MHz, d6-DMSO): 12.85 (S, COOH); 7.91 (d, J=8.3, 2 arom. H); 7.42 (d, J=8.3, 2 arom.H); 4.96, 4.88 (2 s-like; C═CH2); 4.51 (s, —OCH2—C6H4); 3.90 (s, CH2O); 1.69 (s, CH3). 13C-NMR (100 MHz, d6-DMSO): 167.12 (—C═O); 143.60; 141.98; 129.74; 129.32 (2 arom.C); 127.09 (2 arom.C); 111.74; 73.50; 70.52; 19.29.