Hydrogen Peroxide → Tinuvin 123

HRID 1261748

反応式

HRID 1261748 の反応式
[C:1]([O:25][CH:26]1[CH2:31][C:30]([CH3:33])([CH3:32])[N:29]([OH:34])[C:28]([CH3:36])([CH3:35])[CH2:27]1)(=[O:24])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10]([O:12][CH:13]1[CH2:18][C:17]([CH3:20])([CH3:19])[N:16]([OH:21])[C:15]([CH3:23])([CH3:22])[CH2:14]1)=[O:11].OO.C(=O)[CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH3:47].[OH-].[Na+]>C1(C)C=CC=CC=1.C(O)(C)(C)C.C(O)(=O)C>[C:1]([O:25][CH:26]1[CH2:27][C:28]([CH3:36])([CH3:35])[N:29]([O:34][CH2:47][CH2:46][CH2:45][CH2:44][CH2:43][CH2:42][CH2:41][CH3:40])[C:30]([CH3:33])([CH3:32])[CH2:31]1)(=[O:24])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10]([O:12][CH:13]1[CH2:14][C:15]([CH3:22])([CH3:23])[N:16]([O:21][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8])[C:17]([CH3:19])([CH3:20])[CH2:18]1)=[O:11]

参加物

7

反応物 4

HCID 784Hydrogen PeroxideHCID 14798Sodium HydroxideHCID 31289NonanalHCID 11272241Bis(1-hydroxy-2,2,6,6-tetramethyl-4-piperidinyl)decandioate

生成物 1

HCID 3592789Tinuvin 123

試薬・触媒・溶媒 2

HCID 176Acetic Acid溶媒HCID 22595558Toluene tert-butyl alcohol溶媒

反応条件

温度
40 °C

実験手順

10.0 g Bis(1-oxyl-2,2,6,6-tetramethylpiperidin-4-yl) sebacate (Prostab 5415, commercial product of Ciba Specialty Chemicals Inc.) are dissolved in 40 ml toluene/tert-butanol (2:1) and 8 g 50% aqueous hydrogen peroxide are added, followed by 18 ml nonanal, 0.1 ml acetic acid and 0.15 g CuCl2. The reaction mixture is stirred for 2 h at 25-25° C. and afterwards for 10 h at 40° C. The mixture is poured into 100 ml 0.1 N NaOH and subsequently extracted with methylene chloride. The organic phase is washed twice with water and then with sat. sodium chloride solution and dried over sodium sulfate. The organic phase is removed in vacuo and the residue subjected to column chromatography on silica gel to afford 5.4 g of product.

後処理

  1. extractionsubsequently extracted with methylene chloride
  2. washThe organic phase is washed twice with water
  3. dry with materialwith sat. sodium chloride solution and dried over sodium sulfate
  4. customThe organic phase is removed in vacuo

出典と根拠

ORDレコード
ord-f499ab08a37b4d85b2efc98f72897fe2
出典データセット
uspto-grants-2013_06
特許番号
US08471031B2

関連ノート

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